A 14-year-old female patient enters the office and complains about frequent urination. – 2020 | 2021

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Question: A 14-year-old female patient enters the office and complains about frequent urination. she is also thirsty and has some sleep issues. these symptoms make her feel nervous and on edge. blood glucose level in this patient is normal. which hormone might be involved and why?

Answer: Antidiuretic hormone (ADH); Hyposecretion of ADH causes frequent urination and dehydration.

Explanation: The antidiuretic hormone is released in blood by the posterior pituitary gland and serves to stimulate the water reabsorption at the collecting duct of kidneys. It results in the formation of concentrated urine and lesser loss of water from the body. ADH is released in the blood when the person is dehydrated or does not intake enough water.

Hyposecretion of ADH results in the production of a copious amount of urine and loss of lots of water from the body. The person feels thirsty due to lower water levels of the body and develops insomnia. Therefore, the given symptoms of the patient are due to the insufficient secretion of ADH from the posterior pituitary.

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